Market Insights
The global market for antihistamines is expected to grow at 8.7% CAGR during the forecast period from 2018 to 2026. Histamine is a key intermediary of instant hypersensitivity reactions acting locally and helping with vasodilation, smooth muscle contraction, high vascular permeability, inflammation, and edema. Antihistamines are representative of a class of drugs that inhibit the receptors for histamine type 1 (H1). The H1 receptor is present on the smooth muscles of the bronchi, gastrointestinal tract, uterus, and large blood vessels.
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Major antihistamine use has been observed in the treatment of symptoms such as allergic conditions such as itching, runny nose, nasal stuffiness, hives, teary eyes, dizziness, cough, and nausea. A few common side effects observed due to antihistamines are sedation, impaired motor function, dry mouth and throat, dizziness, blurred vision, constipation, and urinary retention. However, modern drug development technologies have helped to reduce the side effects of antihistamines mentioned above for a few decades.
The two classes of antihistamines are first-generation and second-generation antihistamines. The first-generation antihistamines are made up of drugs such as alimemazine, clemastine, chlorphenamine, hydroxyzine, cyproheptadine, ketotifen, promethazine, and others. Drugs such as ketirizine, acrivastine, desloratadine, levocetirizine, fexofenadine, and loratadine. In 2017, the second-generation antihistamine segment was identified as the largest market as it is used as the first line of action in diseases such as urticaria & common cold, and modern drug development technologies have helped to enhance the activity of second-generation antihistamines such as levocitirizine has been developed from cetirizine to reduce dizziness caused by cetirizine. Technology support is therefore expected to develop the therapeutic effect of second generation antihistamines in the near future.
There are several applications of antihistamines such as allergic rhinitis, conjunctivitis, hives, atopic dermatitis, anaphylaxis, and others (angioedema, pruritus, and others). Allergic rhinitis and urticaria together accounted for more than 50% of the market share in 2017 due to the highest global prevalence of disease and increased awareness and accessibility of disease diagnosis and treatment. According to the American Academy of Allergy Asthma & Immunology (AAAAI), global allergic rhinitis affects about 10% to 30% of the population every year. Thus, the prevalence of diseases determines the market demand for antihistamines.
The global market for antihistamines is experiencing enormous competition due to the presence of several national and international market players. Since most drugs are generic and available through a counter that makes the antihistamines market more competitive.
Key Market Movements
List of Companies Covered:
Market Segmentation:
By Antihistamines Type Segment
By Application Segment
By Geography Segment Type
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